Table 1.
Summary of changes in animal weight, bacterial shedding prior to housing, and transmission failures by transmission chain
| Treatment | Transmission chain | Weight change (%) | Viable counts prior to co-housing (CFUa g−1 stool) | Transmission failures | |||
|---|---|---|---|---|---|---|---|
| At peak of infection (Median [range]) | At recovery (Median [range]) | Median (range) | Minimum | Maximum | |||
| Nalidixic Acid | N1 | −0.80 (12.78) | 1.71 (12.76) |
1.10 × 109 (2.61 × 109) |
5.83 × 107 | 2.67 × 109 | None |
| N2 | −0.96 (11.82) | 2.57 (10.93) |
6.84 × 108 (2.92 × 109) |
9.00 × 106 | 2.93 × 109 | One failure: M5 | |
| N3 | 0.00 (8.61) | 3.43 (15.38) |
6.25 × 108 (3.94 × 109) |
6.33 × 107 | 4.00 × 109 | One failure: M20 | |
| N4 | −0.29 (11.19) | 3.75 (20.40) |
7.67 × 108 (2.98 × 109) |
1.58 × 107 | 3.00 × 109 | None | |
| N5 | 1.11 (19.08) | 3.17 (12.38) |
4.17 × 108 (2.42 × 109) |
8.17 × 107 | 2.50 × 109 | Two failures: M7, M15 | |
| Water | W1 | −0.27 (9.22) | 2.87 (11.82) |
6.50 × 108 (2.29 × 109) |
9.00 × 107 | 2.38 × 109 | None |
| W2 | 0.00 (6.61) | 4.01 (13.20) |
7.00 × 108 (5.13 × 109) |
2.00 × 108 | 5.33 × 109 | One failure: M6 | |
| W3 | −0.26 (7.22) | 2.79 (8.30) |
4.33 × 108 (2.49 × 109) |
6.83 × 106 | 2.50 × 109 | Two failures: M3, M7 | |
| W4 | 0.58 (9.40) | 3.28 (7.46) |
8.33 × 108 (3.32 × 109) |
9.83 × 106 | 3.33 × 109 | Two failures: M7, M18 | |
| W5 | 0.54 (12.77) | 3.43 (16.59) |
7.83 × 108 (2.50 × 109) |
8.50 × 107 | 2.58 × 109 | Two failures: M3, M9 | |
Key: aCFU colony forming units.