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. 2023 Oct 31;9:404. doi: 10.1038/s41420-023-01685-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Mouse hippocampal neurons were isolated, cultured, and detected using NeuN/MAP2 IF staining. B The qRT-PCR results suggested that NTRK1 in mouse hippocampal neurons was successfully downregulated upon transfection with the NTRK1 shRNA. n = 3. C, D The NeuN IF staining results indicated that NTRK1 silencing reduced the number of NeuN-positive mouse hippocampal neurons. n = 3. E The CCK-8 assay revealed that NTRK1 silencing attenuated the viability of mouse hippocampal neurons. n = 6. F, G TUNEL staining indicated that NTRK1 silencing intensified the apoptosis of mouse hippocampal neurons. n = 3. **P < 0.01.