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. 2023 Oct 31;13:18763. doi: 10.1038/s41598-023-45976-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differential gene expression analysis based on m5C methylation patterns and EMT status in HNSCC. (a) Volcano map of DEGs in different m5C clusters; (b) Volcano map of DEGs in different EMT statuses; (c) Venn diagram depicting 123 core DEGs in different m5C clusters and EMT groups; (d) GO enrichment analysis displaying the biological functions of core DEGs.