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. 2023 Oct 20;23:100841. doi: 10.1016/j.mtbio.2023.100841

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© 2023 The Authors. Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — GelMA and exosome concentration screening. (A) The influence of 10 %, 15 %, and 20 % GelMA concentrations on cell viability was assessed through Calcein-AM/PI staining. (B) CCK-8 assay revealed the optical density (OD) values of each group on days 1, 3, 5, and 7. (C) Transwell experiment assessed the effect of different exosome concentrations on cell migration. (D) The angiogenesis assay evaluated the impact of different exosome concentrations on endothelial cell vessel formation. (E) Quantification of migrated cells in the Transwell assay showed that 50 μg/mL and 100 μg/mL exosomes significantly promoted endothelial cell migration. (F) Statistical analysis of angiogenesis performance. (G) CCK-8 assay examined the influence of different exosome concentrations on cell proliferation, analyzing the OD values of each group on days 1, 3, 5, and 7. *p < 0.05; **p < 0.01.