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. 2023 Aug 16;29(21):4492–4503. doi: 10.1158/1078-0432.CCR-23-0290

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©2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 6. Common genes and pathways shared by both PDX models in progression vs. stable tumors. A, The 3 downregulated and 3 upregulated differentially expressed genes shared between both models. B, Heat map of the 6 differentially expressed genes shared between CM07 and CM14. C, The number of canonical pathways identified from each model and the number of pathways shared between both models. D, The 5 pathways that are shared between CM07 and CM14 progressing tumors. — Common genes and pathways shared by both PDX models in progression vs. stable tumors. A, The 3 downregulated and 3 upregulated differentially expressed genes shared between both models. B, Heat map of the 6 differentially expressed genes shared between CM07 and CM14. C, The number of canonical pathways identified from each model and the number of pathways shared between both models. D, The 5 pathways that are shared between CM07 and CM14 progressing tumors.