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. 2023 Sep 8;13(11):2339–2355. doi: 10.1158/2159-8290.CD-23-0383

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©2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 4. Combinations of SHP2 with immune checkpoint inhibitors currently tested in the clinic (top). Schematic model of the changes occurring in the tumor microenvironment upon modulation of SHP2 activity (bottom). Created with BioRender.com. — Combinations of SHP2 with immune checkpoint inhibitors currently tested in the clinic (top). Schematic model of the changes occurring in the tumor microenvironment upon modulation of SHP2 activity (bottom). Created with BioRender.com.