Table 2.
Provoking factors and symptoms of hypersensitivity reactions in Hungarian patients with C1-INH-HAE
| Type of hypersensitivity | Number of patients | Provoking factors (number of patients) | Symptoms (number of patients) |
|---|---|---|---|
| Pollen hypersensitivity | 27 | No specific questions were asked | No specific questions were asked |
| Contact sensitivity | 24 | Metal (10) Detergent, rinsing (9) Cosmetics (7) Latex gloves (2) Balsam of Peru (1) Cement (1) Chemicals (1) Diluent (1) Disinfecting cloth (1) Hydrocolloid (1) Oil (1) Paint (1) |
Itching (16) Erythema (13) Urticaria (8) Eczema (7) Edema (5) Rash (1) |
| Food hypersensitivity | 23 | Dairy products (7) Gluten (6) Nuts (5) Tomato (4) Walnut (3) Garlic (3) Coffee (2) Mushroom (2) Onion (2) Crab (1) Egg (1) Fish (1) Fructose (1) Honey (1) Kiwi (1) Orange (1) Peach (1) Poppy seed (1) Red food coloring (1) Sesame (1) Sheep curd (1) Smoked food (1) Sodium benzoate (1) Soy (1) Strawberry (1) |
Bloating (9) Abdominal pain (5) Subcutaneous or submucosal edema (4) Diarrhea (3) Itching of the skin (3) Itching of the throat (3) Erythema (2) Rash (2) Dysphagia (1) Fainting (1) Rhinorrhea (1) |
| Insect sting hypersensitivity | 21 | Bee (9) Mosquito (9) Wasp (8) Horse fly (1) Spider (1) |
Edema (19) Erythema (12) Itching (6) Burning sensation (2) |
| Pet hypersensitivity | 16 | Cat (10) Dog (8) Horse (3) Fish (1) |
Sneezing (7) Itching of the eye (6) Itching of the skin (4) Nasal congestion (4) Rhinorrhea (4) Erythema (2) Itching of the throat (2) Tearing up (2) Blister (1) Dyspnea (1) Itching of the nose (1) |
| Drug hypersensitivity | 15 | β-lactam antibiotics (10) Other antibiotics (6) NSAIDs (2) Alprazolam (1) Dequalinium chloride (1) Glucosamine sulfate (1) Sumatriptan (1) |
Rash, including urticaria (9) Itching (4) Dyspnea (3) Edema (2) Abdominal pain (1) Anxiety (1) Cough (1) Diarrhea (1) Dysphagia (1) Heat wave (1) Laryngeal edema (1) Palpitation (1) “Skin symptoms” (1) Vertigo (1) |
| Dust mite hypersensitivity | 6 | Not applicable | No specific questions were asked |
| Mold hypersensitivity | 2 | Not applicable | No specific questions were asked |
Abbreviations: NSAID – Non-steroid anti-inflammatory drug.