Table 4.
Food provoking HAE attacks
| Patient | Food | HAE symptoms | Food hypersensitivity? |
|---|---|---|---|
| 23 years old female | Coffee, alcohol, milk | SC edema | No |
| 33 years old female | Spicy or fatty food | Abdominal pain | No |
| 33 years old female | Strawberry, nuts, walnut | SC edema | No |
| 35 years old female | Very fatty food | GI edema | Yes (orange, strawberry, onion, fructose) |
| 35 years old female | Shallots | Abdominal pain | No |
| 37 years old female | Gluten | GI edema | Yes (gluten, milk) |
| 41 years old female | Beans, cucumber | GI edema | No |
| 43 years old female | Garlic, mushroom | GI edema, vomiting | Yes (mushroom) |
| 43 years old female | Orange, nuts, walnut | SC edema, erythema | No |
| 48 years old female | Walnut, smoked food, sesame | GI edema | Yes (walnut, garlic, smoked food, soy, sesame) |
| 48 years old female | Nuts, onion, garlic, mushroom | Abdominal pain, malaise | Yes (kiwi, sheep curd) |
| 50 years old female | Orange, walnut, onion | Burning sensation in the mouth, then GI edema | No |
| 51 years old female | Nuts, walnut, onion, garlic, purple onion, sunflower seeds | Abdominal pain | No |
| 55 years old female | Tomato, strawberry, nuts, walnut, onion, garlic, mushroom, paprika, kiwi, pomegranate | SC edema, erythema | No |
| 58 years old female | Nuts, onion | GI edema | No |
| 62 years old female | Walnut, mushroom, gluten | Headachea | No |
| 65 years old female | Onion | Abdominal pain, vomiting | No |
| 75 years old female | Onion | Bloating | No |
| 29 years old male | Leek, camembert | GI edema | No |
| 35 years old male | Dill, fatty food | Abdominal pain | Yes (gluten) |
| 35 years old male | Onion | Bloating, vomiting, diarrhea | No |
| 36 years old male | Tomato, onion, garlic, corn, milk | GI edema | Yes (tomato, onion, garlic, milk) |
| 37 years old male | Nuts, coffee, cola | GI edema | Yes (nuts, gluten) |
| 58 years old male | Dairy products | GI edema | No |
Abbreviations: HAE – hereditary angioedema; GI – gastrointestinal; SC – subcutaneous.
a
There are data in the literature40, 41, 42 listing headaches as a possible, although rare, symptom of HAE attacks. We also have some patients with headaches who did not react to analgesics but were relieved after admission of C1-inhibitor. Therefore, we have accepted this patient's symptoms as an HAE attack caused by these foods.