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General epigenetic characteristics changes in the two groups. (A) Changes in the appearance of mice between the two groups. The hair of aging mice became white and sparse. (B) The body weight increased but grip (C) decreased in the WTA group. The serum levels of ALT (D) and AST (E) increased with age, but the TG (F) and TC (G) levels have no significant changes in the two groups. WTA: wild-type aging, WTY: wild-type young. (***) P < 0.05, n = 10 per group.
