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. 2023 Oct 19;9(11):e21011. doi: 10.1016/j.heliyon.2023.e21011

Fig. 8.

Fig. 8

Network analysis of two omics. (A) Venn diagram of the KEGG pathways in two omics. (B) Level 2 of common pathways in two omics. (C) The histograms of the first ten KEGG pathways with the most proteins and metabolites annotated concurrently in the common pathway. (D) Correlation coefficient matrix heat map with cancer-related proteins and metabolites (rectangle's number: the correlation value, blue: positive correlation, red: negative correlation; the darker the color, the stronger the correlation). (1: P28028_S[Phospho(STY)]PQKPIVR_2, 2: P30115_FLQPGS[Phospho(STY)]QR_2, 3: P07901_ESDDKPEIEDVGS[Phospho(STY)]DEEEEEKK_3, 4: P07901_DKEVS[Phospho(STY)]DDEAEEK_2, 5: B2RXY7_KFS[Phospho(STY)]GDVVLAAR_2, 6: P26151_ANS[Phospho(STY)]FQQVR_2, 7: Q58E70_EQAEAEVAS[Phospho(STY)]LNR_2, 8: Q80U72_NS[Phospho(STY)]LESISSIDR_2, 9: Q8C8R3_S[Phospho(STY)]PQGLELPLPNR_2, 10: A0A068EW80_ATS[Phospho(STY)]PPHLDGTSNPESTVPEKK_3, 11: F6ZDS4_Q[Gln- > pyroGlu]TPQAPQS[Phospho(STY)]PR_2, 12: Q3UW87_VVSRDETVS[Phospho(STY)]DE_2, 13: E9Q4Y0_GGDTS[Phospho(STY)]DTESSIIIR_2, 14: Q03265_TGTAEMSS[Phospho(STY)]ILEER_2, 15: Q03265_AVDS[Phospho(STY)]LVPIGR_2, a: 1-Stearoyl-2-arachidonoyl-sn-glycerol, b: l-Malic acid, c: Progesterone, d: Malate, e: Phenylalanine, f: dl-Glutamic acid) (E) Network interaction diagram between cancer-related proteins and metabolites. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)