. 2023 Aug 21;4(11):926–941. doi: 10.1039/d3cb00127j

1 forms a selective interaction with Fe³⁺ detectable by HRMS. Binding of 1 to a selection of biologically relevant metals was monitored by ESI-HRMS on a Synapt G2-Simass spectrometer. 1 bound strongly and selectively to Fe³⁺, with some weaker binding to Mn²⁺.

Adduct	MS peak (m/z)	Species	Error (ppm)
1	359.0872	[M + H]⁺	−0.6
1 + Fe²⁺	359.0879	[M + H]⁺	1.4
1 + Fe³⁺	411.9980	[M − 2H + Fe³⁺]⁺	−1.9
1 + Mn²⁺	412.0089	[M − H + Mn²⁺]⁺	−2.2
1 + Zn²⁺	359.0867	[M + H]⁺	−1.9
1 + Mg²⁺	359.0869	[M + H]⁺	−1.4
1 + Ga³⁺	359.0881	[M + H]⁺	1.5
1 + mix	411.9992	[M − 2H + Fe³⁺]⁺	−1.0

1 forms a selective interaction with Fe3+ detectable by HRMS. Binding of 1 to a selection of biologically relevant metals was monitored by ESI-HRMS on a Synapt G2-Simass spectrometer. 1 bound strongly and selectively to Fe3+, with some weaker binding to Mn2+.