Inhibition of 1-sensitive ThrRSs requires an intact catechol group. Half maximal inhibitory concentrations (IC₅₀s) for each compound with each of the ThrRSs tested in this study.

Compound	Protein	IC50 (nM)
1	EcThrRS	35 ± 4
	PfThrRS	4.3 ± 0.4
	ObaO	No inhibition
2	EcThrRS	3700 ± 700
	PfThrRS	1600 ± 300
3	EcThrRS	930 ± 80
	PfThrRS	2500 ± 800
4	EcThrRS	No inhibition
	PfThrRS	No inhibition