TABLE 3.
Results of cross‐sectional, test–retest, and longitudinal analysis.
Cross‐sectional | Test–retest (<1 year) | Longitudinal (>1 year) | |||||||
---|---|---|---|---|---|---|---|---|---|
MAE (years) | r | r, PAD | MAD (years) | Adj MAD (years) | ICC (95% CI) | ICC PAD (95% CI) | Adj MAD (years) | Beta (95% CI) | |
brainageR | 4.04 | 0.96** | −0.13* | 1.27 | 1.2 | 0.98 (0.98–0.99) | 0.94 (0.92–0.96) | 1.82 |
1.17 (0.68–1.67) |
DeepBrainNet | 6.13 | 0.89** | −0.43** | 4.25 | 4.24 | 0.57 (0.44–0.68) | 0.25 (0.08–0.41) | 4.93 | 1.93 (0.8–3.05) |
brainage | 6.39 | 0.89** | −0.59** | 2.32 | 2.35 | 0.94 (0.91–0.96) | 0.91 (0.87–0.94) | 2.88 | 0.65 (−0.47 to 1.77) |
ENIGMA | 9.54 | 0.66** | −0.59** | 6.05 | 6.0 | 0.65 (0.53–0.74) | 0.69 (0.58–0.77) | 6.49 |
1.47 (−1.12 to 4.07) |
pyment | 3.56 | 0.97** | −0.31** | 1.18 | 1.17 | 0.98 (0.98–0.99) | 0.94 (0.91–0.96) | 1.7 | 0.84 (0.44–1.24) |
mccqrnn | 4.46 | 0.95** | −0.46** | 1.76 | 1.73 | 0.97 (0.96–0.98) | 0.92 (0.89–0.94) | 1.98 | 1.14 (0.60–1.67) |
Note: Adj, adjusted; Beta, slope of linear mixed effects model fitted to assess the relation between progressed predicted age and progressed chronological age; r, Pearson's correlation coefficient, associated p‐value.
p < .01;
p < .005.