TABLE 3.
Mean [11C]‐PBR28 standardized uptake value ratio (SUVR) by region of interest (ROI).
| Cancer survivors | Healthy controls | Comparison | ||
|---|---|---|---|---|
| Whole brain | .905 (.030) | .890 (.045) | p = .389 | |
| Accumbens | .944 (.125) | .957 (.045) | p = .759 | |
| Amygdala | .981 (.122) | 1.001 (.076) | p = .659 | |
| Basal forebrain | 1.019 (.114) | 1.024 (.057) | p = .913 | |
| Brainstem | 1.083 (.185) | 1.153 (.072) | p = .277 | |
| Caudate | .771 (.055) | .715 (.058) | p = .042 | |
| Cingulate | .965 (.046) | .968 (.041) | p = .874 | |
| Entorhinal | 1.015 (.058) | .956 (.090) | p = .0.98 | |
| Frontal | .906 (.031) | .908 (.066) | p = .908 | |
| Hippocampus | .984 (.082) | .985 (.053) | p = .951 | |
| Insula | .958 (.068) | .966 (.037) | p = .733 | |
| Occipital | 1.005 (.051) | .946 (.049) | p = .018 | |
| Pallidum | .947 (.132) | .957 (.057) | p = .836 | |
| Parahippocampus | .965 (.040) | .926 (.064) | p = .116 | |
| Putamen | .950 (.081) | .924 (.057) | p = .429 | |
| Temporal | .973 (.020) | .939 (.039) | p = .021 | |
| Thalamus | 1.021 (.125) | 1.067 (.037) | p = .285 | |
| Ventral DC | .986 (.159) | 1.047 (.075) | p = .283 | |
| Lateral ventricle | .667 (.122) | .620 (.151) | p = .451 | |
| Whitematter | .842 (.052) | .832 (.052) | p = .667 | |
| CSF third ventricle | .934 (.123) | 1.031 (.160) | p = .148 | |
| CSF fourth ventricle | .893 (.071) | .980 (.094) | p = .032 | |
Note: Values in bold font highlights statistically significant findings.