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. 2023 Oct 20;79(Pt 11):980–991. doi: 10.1107/S2059798323007611

Table 1. Crystallization conditions.

Protein Human DHX9 (150–1150) Dog DHX9 (151–1151) Cat DHX9 (151–1151)
Method Hanging drop Hanging drop Hanging drop
Plate type 24-well 24-well 24-well
Temperature (K) 291 291 291
Protein concentration (mg ml−1) 8 8 8
Buffer composition of protein solution 20 mM HEPES, 300 mM NaCl, 2 mM TCEP pH 7.5, 5 mM ADP, 50 mM MgCl2 20 mM HEPES, 300 mM NaCl, 2 mM TCEP pH 7.5, 5 mM ADP, 50 mM MgCl2 20 mM HEPES, 300 mM NaCl, 2 mM TCEP pH 7.5, 5 mM ADP, 50 mM MgCl2
Composition of reservoir solution 200 mM lithium sulfate, 100 mM MES pH 6, 20%(w/v) PEG 4000 200 mM lithium sulfate, 100 mM MES pH 6, 20%(w/v) PEG 4000 150 mM ammonium sulfate, 100 mM Tris pH 8, 19%(w/v) PEG 4000
Volumes of protein/reservoir in crystallization drop (µl) 1.5/1.5 1.5/1.5 1.5/1.5
Volume of reservoir (µl) 500 500 500