Figure 4.
RNA Levels of proinflammatory cytokines in MVA-S(3P)-vaccinated hamsters. IL-6, MX-2, IP-10, and IFN-γ mRNA levels were detected by RT-qPCR in lungs obtained 4 days post-SARS-CoV-2 infection (n = 10/group). Mean RNA levels and SEM are depicted. The log2-fold change compared to the RNA levels of vehicle control is plotted. Statistical significance between groups was calculated using an ordinary one-way ANOVA of transformed data followed by Tukey’s multiple comparison test (*p<0.033, ***p < 0.0002, ****p<0.0001).