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. 2023 Oct 31;64(13):48. doi: 10.1167/iovs.64.13.48

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Figure 1. — Differential expression of ECM related genes between the central cornea and limbus in mice. Heatmaps showing differential expression ECM components (A), heparan sulfate biosynthetic enzyme (B), keratan sulfate biosynthetic enzyme (C), chondroitin sulfate biosynthetic enzyme (D), collagen and laminin (E), and matrix metalloproteinase (F) genes between the central cornea versus the limbus. The heatmap representing the color-coded fold expression for each heatmap is shown underneath each heatmap. Darker blue colors represent a higher fold difference. Heatmaps to the left indicate genes that are upregulated in the central cornea when compared to the limbal region, and heatmaps to the right indicate genes that are upregulated in the limbus when compared to the central cornea.