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. 2023 Oct 18;14:1271449. doi: 10.3389/fimmu.2023.1271449

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Copyright © 2023 Zelba, Rabsteyn, Bartsch, Kyzirakos, Kayser, Seibold, Harter, Latzer, Hadaschik, Battke, Golf, Rettig and Biskup

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune monitoring result for peptide 25 (LQQIFESQHMKFSEIPQ; SMARCD1:NM_003076.5:c.1052G>A:p.R351H) from M13. Vaccine-induced mutated SMARCD1-specific CD4+ T-cells (upper row; y-axis: TNF-α; x-axis: CD154) and CD8+ T-cells (lower row; (y-axis: TNF-α; x-axis: IFN-γ) are shown. T-cells were either mock restimulated (negative control, NC: (left)), peptide-restimulated cells (middle), or Cytostim-stimulated sample (positive control, PC: (right)). Numbers indicate frequency within all CD4+ or CD8+ T-cells, respectively.