Table 1. Eligibility criteria–bleeding disorders and conditions.
| Bleeding Disorder | Diagnosis |
|
|---|---|---|
| Congenital disorders of hemostasis | Hemophilia A | --- |
| Hemophilia B | --- | |
| Von Willebrand disease (VWD) | --- | |
| Disorders of fibrinogen and fibrinolysis | Afibrinogenemia Dysfibrinogenemia Hypodisfibrinogenemia |
|
| Platelet function defects | Bernard-Soulier syndrome Gray platelet syndrome May-Hegglin anomaly Storage pool disorders (Wiskott-Aldrich syndrome, Chediak-Higashi, Hermansky-Pudlak) Glanzmann thrombasthenia |
|
| Rare bleeding disorders (RBDs)/ rare inherited coagulation disorders (RICDs)/Rare coagulation deficiencies (RCDs) |
--- | |
| Acquired disorders of hemostasis | Antithrombotic therapy | see Table 2 |
| Acquired inhibitors of coagulation (“acquired hemophilia”) |
--- | |
| Consumptive coagulopathy/ Disseminated Intravascular Coagulation (DIC) |
--- | |
| Liver disease Cirrhosis |
--- | |
| Acquired disorders of platelet function |
Uremic platelet dysfunction Immune thrombocytopenia (ITP) Platelet dysfunction secondary to cardiopulmonary bypass |
|
| Thrombocytopenia | --- | |
| Acquired von Willebrand syndrome (AVWS) | --- | |
| Iatrogenic bleeding | Surgical bleeding Procedural bleeding |
--- |
| Human volunteer bleeding models | Skin punch biopsy |