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. 2023 Nov 1;13:18848. doi: 10.1038/s41598-023-45870-1

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of LDL versus LPS on gene expression in human macrophage models: the effect of native LDL on the mRNA expression of IL1B (A), NLRP3 (B), MCP1 (C), IL10 (D), LDLR (E) and CD36 (F) in hMDM and THP-1 derived macrophages using baseline medium supplemented with subject own LDL (0.1–1.2 g/L apoB) or LPS (0.01 μg/mL) over 4 h. Data was analyzed by mixed-method analyses, *for p < 0.05 and **for p < 0.01 compared to baseline medium alone.