Table 3.
Differences in WAT IL-1β-secretion induced by the 7-incubation conditions with medium, LDL, LPS and/or ATP in subjects with low-apoB (N = 13) and high-apoB (N = 16) before and after adjustment for covariates.
| Adjusted for | Group-effect p value |
|---|---|
| No adjustment | 0.003 |
| Body composition | |
| BMI | 0.005 |
| Total body fat | 0.006 |
| BMI and waist/hip circumference ratio | 0.007 |
| Total body fat and android/gynoid ratio | 0.008 |
| Fasting plasma lipoprotein-related parameters | |
| Plasma cholesterol | 0.009 |
| Plasma LDL-C | 0.005 |
| Plasma HDL-C | 0.003 |
| Plasma NEFA | 0.004 |
| LOG10 plasma TG | 0.006 |
| Plasma apoB | 0.079 |
| Plasma PCSK9 | 0.004 |
| Plasma apoB/PCSK9 | 0.029 |
| Plasma LDL-C/apoB | 0.006 |
| Energy intake and expenditure | |
| Basal metabolic rate | 0.003 |
| Daily energy intake | 0.001 |
| % carbohydrate intake | 0.022 |
| % fat intake | 0.011 |
| % saturated fat intake | 0.005 |
| LOG10 fasting baseline WAT mRNA | |
| PPARG | 0.005 |
| ADIPOQ | 0.002 |
| HMGCR | 0.005 |
| SREBP1C | 0.004 |
| SREBP2 | 0.009 |
| CD36 | 0.007 |
| LDLR | 0.004 |
| MCP1 | 0.005 |
| ADGRE1 | 0.008 |
| NLRP3 | 0.007 |
| IL1B | 0.003 |
| CASP1 | 0.002 |
| IL10 | 0.005 |
| Fasting baseline WAT protein | |
| Pro-IL-1β | 0.003 |
| % plasma phospholipid FA | |
| % total saturated FA | 0.007 |
| % total monounsaturated FA | 0.008 |
| % total omega-3 FA | 0.007 |
| % total omega-6 FA | 0.009 |
| % total polyunsaturated FA | 0.009 |
Significant values are in bold.
Data analyzed by 2-way RM-ANOVA. N.B. Only subjects with complete WAT IL-1β-secretion profiles induced by the 7-incubation conditions were used in this analysis.