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. 2023 Nov 2;11:58. doi: 10.1038/s41413-023-00292-7

Table 1.

The effect of genetically predicted FTH1 mRNA expression on hand OA

Exposure N SNPs MR Method OR (95% CI) P value
FTH1 mRNA expression 133 IVW 1.07 (1.02–1.11) 0.005
Weighted median 1.09 (1.00–1.18) 0.046
MR Egger 1.08 (1.00–1.18) 0.046
MR-PRESSO 1.07 (1.02–1.11) 0.006

OA osteoarthritis, N SNPs number of single-nucleotide polymorphisms, IVW inverse-variance weighted, MR Mendelian randomization, OR odds ratio, CI confidence interval