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The effect of genetically predicted FTH1 mRNA expression on hand OA
| Exposure | N SNPs | MR Method | OR (95% CI) | P value |
|---|---|---|---|---|
| FTH1 mRNA expression | 133 | IVW | 1.07 (1.02–1.11) | 0.005 |
| Weighted median | 1.09 (1.00–1.18) | 0.046 | ||
| MR Egger | 1.08 (1.00–1.18) | 0.046 | ||
| MR-PRESSO | 1.07 (1.02–1.11) | 0.006 |
OA osteoarthritis, N SNPs number of single-nucleotide polymorphisms, IVW inverse-variance weighted, MR Mendelian randomization, OR odds ratio, CI confidence interval
