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. 2023 Aug 30;31(11):1251–1260. doi: 10.1038/s41431-023-01445-2

Fig. 4. Cux1 heterozygosity results in increased seizure susceptibility in mice.

Fig. 4

A Identification of stages of seizure in a kainate-induced model of epilepsy. Photographs show representative behaviors from the less severe to the most, progressing from non-convulsive to convulsive seizure stages (R1-R6). B The maximum stage of seizure was reached in WT and Cux1+/− mice during the first 2 h of kainate induction. Data show mean ± SEM (n = 10 per condition. Mann–Whitney test: P-value WT vs. Cux1+/− ** ≤ 0.01). C Latency to the onset of convulsive stages (R3) in WT and Cux1+/− mice after kainate induction. Data show mean ± SEM (n ≥ 8 per condition. Mann–Whitney test: P-value WT vs. Cux+/− = 0.3478 (n.s.)).