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. 2023 Oct 19;17:1252689. doi: 10.3389/fnins.2023.1252689

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Copyright © 2023 Urushihata, Goto, Kabetani, Kiyozuka, Maruyama, Tsuji, Tada and Satoh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Connectivity changes among brain regions due to SD. Connectivity among 294 regions was estimated for ad libitum sleep animals and SD animals regardless of the method, and mean interregional correlation coefficients (mean r) were obtained for the 14 brain regions. The bar graph shows the mean r between one region and another within that region: (A), isocortex; (B), olfactory areas; (C), hippocampal formation; (D), cortical subplate; (E), striatum; (F), pallidum; (G), thalamus; (H), hypothalamus; (I), midbrain; (J), pons; (K), medulla; (L), cerebellum; (M), fiber tracts; and (N) ventricular systems. Error bars indicate SEM. *p < 0.05; **p < 0.01; and ***p < 0.001 for the difference between ad libitum sleep mice and SD mice by Kolmogorov–Smirnov test.