Figure EV2. ITNKs increase the H3K27Ac at TSS region of pluripotency gene sets.

1. Bar chart indicating the number of peaks and the number of genes at the peak position in these omics‐seq.
2. Bar chart demonstrating the percentage of peaking with a TSS, TSS‐promoter, transcription end site (TES), and other sites in these omics‐seq.
3. Tag density pileups of H3K27Ac peaks in CD8⁺ T cells transduced with sgBCL11B, sgMBD2, or sgCHD4 and CD8⁺ sgCtrl‐transduced T cells. Two individual healthy donors were used for the CUT&Tag assay.
4. Tag density pileups of H3K27Ac peaks at the T‐cell‐activation gene set (see Table EV2) in CD8⁺ T cells transduced with sgBCL11B, sgMBD2, or sgCHD4 and CD8⁺ sgCtrl‐transduced T cells.
5. Tag density pileups of H3K27Ac peaks at the natural‐killer‐cell‐mediated‐immunity gene set (see Table EV3) in CD8⁺ T cells transduced with sgBCL11B, sgMBD2, or sgCHD4 and CD8⁺ sgCtrl‐transduced T cells.
6. Tag density pileups of H3K27Ac peaks at the oxidative‐phosphorylation gene set (see Table EV4) in CD8⁺ T cells transduced with sgBCL11B, sgMBD2, or sgCHD4 and CD8⁺ sgCtrl‐transduced T cells.

Source data are available online for this figure.