Table 2.
Reports of allergenic responses to toxigenic fungi and mycoses associated with cannabis users (excluding those reported in Trullas et al., 2010).
| Species | Diagnosis reported/Study description; Use; Immunosuppressive | Fungal identification method | References | |
|---|---|---|---|---|
| Aspergillus | A. fumigatus | Allergenic response in 28 cannabis smokers; one with systemic aspergillosis, seven with bronchospasm after smoking | Patient tissue samples—Serology | Kagen et al. (1983) |
| A. flavus | Cultured from products (serology) | |||
| A. niger | ||||
| A. fumigatus | Bronchopulmonary aspergillosis; cannabis smoker; and asthma | Patient tissue samples—Serology | Kouevidjin et al. (2003) | |
| Cultured from products | ||||
| A. flavus | ||||
| A. fumigatus | Invasive pulmonary aspergillosis; metastatic colorectal cancer and chemotherapy | Sequencing | Cescon et al. (2008) | |
| A. fumigatus | Chronic pulmonary aspergillosis; daily cannabis smoker; with steroid use | Serology | Gargani et al. (2011) | |
| Chronic pulmonary aspergillosis; daily cannabis smoker | Serology | Gargani et al. (2011) | ||
| A. rugolosa | Chronic necrotizing pulmonary aspergillosis; cannabis via vaporizer daily; diabetes | A. rugolosa confirmed by sequencing | Remington et al. (2015) | |
| A. fumigatus | A. fumigatus (cultured from patient) | |||
| Penicillium sp. | ||||
| A. fumigatus | Disseminated aspergillosis; former cannabis user; HIV + steroids | Cultured from patient | Salam and Pozniak (2017) | |
| Fusarium | Fusarium sp. | Cutaneous fusariosis; hyper-IgE-syndrome + steroids; cannabis grower* | Cultured from patient (microscopy) | Altibi et al. (2020) |
| Alternaria | Al. alternata | Allergenic responses in 316 (11.8% of participants) current cannabis users | Serology | Min and Min (2018) |
| Cryptococcus | Cryptococcus sp., including C. neoformans | Cryptococcal meningitis; daily cannabis smoker; and no evidence of immunodeficiency | Patient cerebrospinal fluid samples—Microscopy and mass spectrometry | Shapiro et al. (2018) |
*Patient’s cannabis plants “died out because of the mold.”