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. 2023 Oct 16;19(16):5275–5289. doi: 10.7150/ijbs.86701

Figure 2.

Figure 2

Omentin-1 inhibited the production of pro-inflammatory cytokines by upregulating IL-4 expression. (A and B) IHC staining showing that IL-1β, IL-6, IL-8, and TNF-α were higher in human OA synovial tissue than in healthy tissue. Scale bar = 100 µm. (C) Gene expression levels in normal and OA synovial tissue samples retrieved from the GEO dataset. (D and E) qPCR analysis showing the gene expression of OASFs treated with omentin-1 or transfected with IL-4 siRNA prior to stimulation using omentin-1, n=6 for each group. * p<0.05 vs controls. # p<0.05 vs omentin-1-treated group.