Table 9.

Expanded Genotypes Analysis results for 5 RF-scored genes identified in the Severe cohort linked to disease signatures of 2 or 3 SNPs (one disease signature contains SNPs associated with two genes)

Target Gene	SNX9	ADIPOQ	DLC1	NOL4	PDE6C
Universally causative minor allele	0	0	0	0	0
Universally protective minor allele	0	3	0	2	2
Minor allele with SNP-specific causative effect	2	0	0	0	0
Minor allele with SNP-specific protective effect	2	3	0	0	2
Minor allele with combination-specific causative effect	0	3	0	2	0
Minor allele with combination-specific protective effect	0	0	0	0	0
Ambiguous/no consistent effect	0	1	2	0	0