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. 2023 Jul 21;45(6):356–368. doi: 10.1055/s-0043-1770931

Chart 1. Regimen of use of misoprostol alone according to gestational age for uterine evacuation in induced abortion/legal abortion.

Gestational age Dosage
Up to 14 weeks misoprostol 800 mcg (vaginally, sublingually, or buccally) every 3 hours
14- 24 weeks misoprostol 400 mcg (vaginally, sublingually, or buccally) every 3 hours
25-28 weeks misoprostol 200 mcg (vaginally, sublingually, or buccally) every 4 hours
Over 28 weeks misoprostol 100 mcg every 6 hours

Source: Krugh M, Maani CV. Misoprostol. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2022 [cited 2022 Dec 15]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539873/ . Morris JL, Winikoff B, Dabash R, Weeks A, Faúndes A, Gemzell-Danielsson K, et al. FIGO's updated recommendations for misoprostol used alone in gynecology and obstetrics. Int J Gynaecol Obstet. 2017;138(3):363-6. doi: 10.1002/ijgo.12181. World Health Organization. Abortion care guideline [Internet]. Geneva: WHO; 2022 [cited 2022 Oct 31]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK578942/pdf/Bookshelf_NBK578942.pdf . 1 17 34