. Author manuscript; available in PMC: 2023 Nov 2.

Published in final edited form as: Clin Genitourin Cancer. 2023 Apr 4;21(4):507.e1–507.e14. doi: 10.1016/j.clgc.2023.03.015

Table 2.

Univariate and MULTIVARIATE COX REGREssion for OS in the Institutional Cohort of Patients Treated With Radical Cystectomy (CUC and SUC Combined).

Overall Survival (From BC Diagnosis)
	UnivaUnivariate		MultivariaMultivariaMultivariate
Variables	HR (95% CI)	P-Value	HR (95% CI)	P-Value
Age ≥65yo	1.57 (1.08–2.27)	.018	1.68 (1.15–2.44)	.007
Sarcomatoid histology	2.60 (1.65–4.09)	<.001	2.36 (1.45–3.84)	.001
ECOG PS≥2	1.93 (1.06–3.50)	.031	2.40 (1.30–4.41)	.005
NAC	0.94 (0.60–1.44)	.76	0.96 (0.66–1.39)	.811
pT≥3	3.04 (2.15–4.30)	<.001	2.23 (1.49–3.36)	<.001
pN≥1	2.59 (1.79–3.75)	<.001	1.75 (1.14–2.70)	.011
LVI at RC	2.47 (1.68–3.62)	<.001	1.38 (0.87–2.19)	.171
Positive margins	1.93 (1.04–3.57)	.038	1.02 (0.51–2.03)	.958

Abbreviations: BC = bladder cancer; CI = confidence interval; CUC = conventional urothelial carcinoma, ECOG PS = eastern cooperative oncology group performance status; HR = hazard ratio; LVI = lymphovascular invasion; NAC = neoadjuvant chemotherapy; pN = pathologic nodal stage; pT = pathologic tumor stage; RC = radical cystectomy; SUC = sarcomatoid urothelial carcinoma.