Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 1;43(44):7351–7360. doi: 10.1523/JNEUROSCI.0282-23.2023

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Weng et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 2. — WMI in the needle ABCS mode. A, Representative H&E staining of brain slices in sham and needle mice six weeks after surgery. Black arrowheads denote cell death in the CC, EC, IC, St, and AC in the left hemisphere in needle mice. B, directionally encoded color (DEC) map of ex vivo DTI six weeks after surgery. The color sphere represents the directionality of the principal axis of diffusion (red = left/right, green = dorsal/ventral, and blue = rostral/caudal). White arrowheads denote anisotropy reduction in the left CC, Cg, EC, IC, St, and Hippo. C, Representative MBP (red) and NF200 (green) staining in sham and needle mice six weeks after surgery (4×). Star represents microinfarct area. D, Representative MBP (red) and NF200 (green) staining (200×) in left CC at different time points after needle surgery. White arrowheads denote axonal demyelination. E, Quantitative analysis of FA in sham and needle mice. FA data in the CC, EC, IC, St, Hippo, Cg, and Fi for both the left and right hemispheres in sham and needle mice were quantitatively measured using DSI Studio and analyzed using one-way ANOVA. Data were expressed as mean ± SEM, n = 3 for sham, n = 5 for needle mice, * represents p < 0.05 versus sham.