Table 2. . Percent positivity for cell lines and patient samples.
Antibodies | Cell lines | Patient samples (by rs1259419 genotype) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
HL-60 (CC) | Molm-13 (CC) | MV4;11 (CT) | K562 (TT) | CD14-CD45dimCD34+ AML progenitor cells | CD14+ monocytes | |||||
CC (n = 5) | CT (n = 5) | TT (n = 4) | CC (n = 5) | CT (n = 5) | TT (n = 4) | |||||
P67.6 | 94.5 | 99.2 | 98.2 | 2.1 | 44.1 | 35.0 | 30.2 | 75.8 | 80.5 | 30.1 |
HL2541 | 3.6 | 2.5 | 17 | 94.4 | 23.0 | 14.3 | 35.9 | 67.7 | 80.1 | 64.5 |
5C11–2 | 0 | 0.01 | 0.04 | 0.04 | 7.5 | 4.4 | 19.1 | 10.7 | 20.0 | 15.6 |
AML: Acute myeloid leukemia; CC: Homozygous dominant; CT: Heterozygous; TT: Homozygous recessive.