A: Cut-plane views during simulation of two fluid-filled compartments separated by a deformable membrane, where each fluid is uniformly initialized with an initial concentration of a species. Particle color indicates species concentration with red as high, yellow and green as intermediate, and blue as low concentration. The membrane contains a particle that actively pumps the species from the lower to the upper compartment. B: Three-dimensional view of initial simulation state. C: Measurements of total species amounts in the lower (blue, circles), upper (red, triangles) and both (green, diamonds) compartments (left-hand vertical axis), and in the channel (magenta, squares, right-hand axis), during simulation.