Table 2.

Multilevel Structural Equation Modeling Results Describing Sex and Condition (200mg CBD, 30mg CBD, Placebo) Differences in Change in Outcomes during the Descending Limb of the BrAC Curve.

	BrAC*100
	Estimate	Posterior SD	Bayesian CI
SBrAC	−1.67	0.59	−2.91, −0.72
S30-P	−0.84	0.25	−1.25, −0.30
S200-P	−0.71	0.31	−1.34, −0.12
S200–30	−0.71	0.31	−1.33, −0.14
SBrAC ← Sex	0.10	0.38	−0.50, 0.93
S30-P← Sex	0.06	0.16	−0.31, 0.34
S200-P← Sex	−0.07	0.20	−0.44, 0.32
S200–30 ← Sex	−0.60	0.18	−0.43, 0.30
	AUQ
	Estimate	Posterior SD	Bayesian CI
SAUQ	−1.38	1.49	−4.53, 1.29
S30-P	−0.19	0.44	−1.07, 0.68
S200-P	−0.50	0.57	−1.65, 0.52
S200–30	−0.44	0.48	−1.45, 0.49
SAUQ ← Sex	−0.12	0.91	−1.78, 1.78
S30-P← Sex	−0.12	0.27	−0.68, 0.39
S200-P← Sex	0.04	0.34	−0.58, 0.72
S200–30 ← Sex	−0.01	0.29	−0.59, 0.56
	SED
	Estimate	Posterior SD	Bayesian CI
SSED	−0.17	1.64	−4.29, 2.13
S30-P	−2.41	1.15	−4.61, −0.09
S200-P	−1.07	1.12	−3.37, 1.03
S200–30	−0.80	1.00	−2.61, 1.50
SSED ← Sex	−0.22	0.92	−1.91, 1.73
S30-P← Sex	0.69	0.75	−0.89, 2.07
S200-P← Sex	−0.19	0.69	−1.43, 1.23
S200–30 ← Sex	−0.30	0.60	−1.70, 0.75
	STIM
	Estimate	Posterior SD	Bayesian CI
SSTIM	0.51	1.42	−2.46, 3.08
S30-P	−2.26	1.17	−4.60, 0.18a
S200-P	−2.38	1.19	−4.46, −0.03
S200–30	−2.62	1.40	−5.42, 0.11a
SSTIM ← Sex	−0.10	0.89	−1.80, 1.65
S30-P← Sex	0.39	0.78	−1.16, 1.90
S200-P← Sex	0.62	0.73	−0.82, 2.01
S200–30 ← Sex	0.55	0.83	−1.01, 2.19
	HA-POS
	Estimate	Posterior SD	Bayesian CI
SHA-POS	−3.09	1.66	−6.68, −0.59
S30-P	−0.46	0.61	−1.58, 0.76
S200-P	−1.17	0.69	−2.51, 0.21a
S200–30	−1.03	0.63	−2.22, 0.22
SHA-POS ← Sex	0.67	0.84	−0.82, 2.47
S30-P← Sex	−0.11	0.41	−0.96, 0.66
S200-P← Sex	0.33	0.44	−0.53, 1.20
S200–30 ← Sex	0.30	0.40	−0.52, 1.03
	LA-POS
	Estimate	Posterior SD	Bayesian CI
SLA-POS	0.86	1.47	−2.79, 2.90
S30-P	−1.09	0.73	−2.39, 0.48
S200-P	−1.13	1.25	−3.86, 1.09
S200–30	−1.00	1.28	−3.71, 1.25
SLA-POS ← Sex	−1.19	0.85	−2.50, 0.70
S30-P← Sex	0.26	0.46	−0.72, 1.08
S200-P← Sex	0.19	0.73	−1.10, 1.72
S200–30 ← Sex	0.12	0.74	−1.20, 1.72

Note: BrAC

^*100 = breath alcohol concentration multiplied by 100 to aid in model convergence; AUQ = alcohol urge questionnaire; STIM = biphasic alcohol effects scale stimulation; SED = biphasic alcohol effects scale sedation; HA-POS = subjective effects of alcohol scale high arousal positive affect; LA-POS = subjective effects of alcohol scale low arousal positive affect; S = random slope, subscript indicates change over time or provides the pairwise comparison for predicting slope from condition (e.g., S_30-P = dummy coded condition predicting the random slope capturing change over time in the outcome for that section of the table); SD = standard deviation; CI = credibility interval.

^aindicates an estimate that was significant based on the p-value but not based on the Bayesian CI. All results are from the model with placebo as the referent group besides effects that compare 30mg to 200mg, which came from the re-run of the model for all pairwise comparisons.