Table 1.

AUC and partial AUCs obtained by ten-fold cross-validation.

Classification	Metric	Method
		Graph embedding	Classification-based
Synergistic-versus-rest	AUC	0.615 ± 0.020	0.556 ± 0.040
	AUC0.5	0.211 ± 0.016	0.164 ± 0.023
	AUC0.2	0.048 ± 0.004	0.033 ± 0.006
Antagonistic-versus-rest	AUC	0.576 ± 0.014	0.550 ± 0.033
	AUC0.5	0.150 ± 0.010	0.159 ± 0.017
	AUC0.2	0.020 ± 0.004	0.024 ± 0.003

Values are means ± SD of 10 iterations, and the significantly better results are highlighted in bold (paired t-test, p < 0.01).

AUC areas under the receiver operating characteristic (ROC) curve.