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. 2023 Oct 4;32:98–123. doi: 10.1016/j.bioactmat.2023.09.017

Table 3.

Decellularized tissue/graft mechanical properties in comparison with the native tissue.

Tissue Mechanical Testing Property Assessed Native Tissue dECM Ref
Trachea
Tensile Testing Elastic Modulus 2.68 MPa 2 MPa [283]
Cartilage
Compression Testing Instantaneous Compressive Modulus 4 MPa 0.6 MPa [284]
Compressive Strength Testing Elastic Modulus 0.36 ± 0.07 MPa 0.55 ± 0.15 MPa [285]
Tension-Torsion Compression Testing Ultimate Tensile Strength 2.10 ± 0.29 MPa 1.90 ± 0.31 MPa [286]
Elastic Modulus 18.40 ± 4.02 MPa 16.49 ± 4.79 MPa
Stress-Relaxation Testing Equilibrium Modulus ∼148 kPa ∼20 kPa [154]
Bone
Unconfined Compression Testing Elastic Modulus 198.2 ± 159.5 MPa 144.9 ± 101.3 MPa [287]
Compression Testing
Three-Point Bending Testing
Elastic Modulus Radius: 7 ± 1 GPa
Ulna: 6 ± 1 GPa
Radius: 7 ± 3 GPa
Ulna: 9 ± 3 GPa
[288]
Compressive Strength Radius: 173 ± 4 MPa
Ulna: 125 ± 24 MPa
Radius: 116 ± 42 MPa
Ulna: 129 ± 39 MPa
Yield Strength Radius: 168 ± 5 MPa
Ulna: 120 ± 26 MPa
Radius: 113 ± 41 MPa
Ulna: 124 ± 40 MPa
Bone-Fibrocartilage-Tendon (BFT) Uniaxial Tensile Testing Elastic Modulus 501.48 ± 91.56 MPa 384.97 ± 86.37 MPa [188]
Ultimate Tensile Strength 53.27 ± 11.84 MPa 45.41 ± 7.05 MPa
Failure Strain at UTS 0.143 ± 0.009 0.129 ± 0.014
Muscle
Stress-Relaxation Testing Tangent Modulus 308 ± 51.1 kPa 218.24.5 kPa [289]
Uniaxial Tensile Testing Elastic Modulus 0.19 ± 0.07 MPa 0.41 ± 0.32 MPa [290]
Ultimate Tensile Strength 0.21 ± 0.08 MPa 1.32 ± 0.85 MPa
Strain at Failure 1.24 ± 0.27 160 ± 0.30
Uniaxial Tensile Testing Elastic Modulus 2.04 ± 0.54 MPa 1.74 ± 0.46 MPa [291]
Ultimate Tensile Strength 0.19 ± 0.03 MPa 0.23 ± 0.04 MPa
Strain at UTS 1.23 ± 0.44 1.38 ± 0.27
Tendon
Tensile Testing Elastic Modulus 299.71 ± 41.67 MPa 210.68 ± 46.43 MPa [292]
Ultimate Tensile Strength 34.67 ± 3.47 MPa 29.69 ± 6.73 MPa
Strain at UTS 15.50 ± 3.12% 19.16 ± 4.58%
Stiffness 25.50 ± 3.71 N/mm 27.40 ± 8.66 N/mm
Ultimate Tensile Stress Testing Yield Strain 8.337 ± 0.142% 7.829 ± 0.442% [293]
Failure Strain 8.712 ± 0.510% 8.851 ± 0.216%
Yield Stress 5.774 ± 0.44 MPa 5.782 ± 0.775 MPa
Failure Stress 6.029 ± 0.414 MPa 6.045 ± 0.759 MPa
Elastic Modulus 76.13 ± 4.12 MPa 70.31 ± 5.91 MPa
Ultimate Load to Failure Testing Ultimate Load 200.39 ± 22.11 N 185.95 ± 7.91 N [294]
Stiffness 44.26 ± 2.96 N/mm 45.99 ± 5.4 N/mm
Aorta
Tensile Testing Elastic Modulus 551.1 ± 152.2 kPa 416.5 ± 72.6 kPa [77]