Skip to main content
. 2023 Oct 2;14(17):3248–3257. doi: 10.7150/jca.88063

Figure 3.

Figure 3

displays how ASPM can regulate EMT to stimulate the invasion and migration of RCC in vitro. Panels a and b depict the migration and invasion capabilities of 769P and CAKI-1 cells with ASPM knockdown, respectively. Panels c and d present the corresponding migration and invasion capabilities of 769P and CAKI-1 cells following ASPM overexpression, respectively. Panel e shows the protein levels of MMP2, β-catenin, and MMP9 in 769P and CAKI-1 cells cells that underwent ASPM knockdown. The symbol (*) signifies a statistically significant difference at P<0.05, while double asterisks (**) indicate a high level of statistical significance at P<0.01. The error bars represent the mean±SD values derived from t-tests.