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. 2023 Sep 7;37(17-18):e24963. doi: 10.1002/jcla.24963

TABLE 2.

Concordance of directly measured LDL‐cholesterol with estimated cholesterol using Friedewald equation, Martin/Hopkins equation, Extended Martin/Hopkins equation, Sampson equation according to TG levels.

DLDL, mg/dL TG < 200 mg/dL TG 200–799 mg/dL
n FLDL EMLDL SLDL p value a n FLDL EMLDL SLDL p value a
<40 26 100.0 100.0 100.0 1.000 6 100.0 100.0 100.0 1.000
40–69 646 84.8 87.3 85.5 <0.001 b 38 84.2 84.2 84.2 1.000
70–99 1947 76.7 78.0 76.6 0.028 c 148 43.9 73.0 66.9 <0.001 f
100–129 2319 75.7 77.7 76.4 0.001 d 204 55.4 73.5 69.6 <0.001 f
130–159 1979 74.7 75.3 76.2 0.093 225 48.0 70.7 60.9 <0.001 g
160–189 784 71.8 72.5 74.7 0.009 e 81 51.9 60.5 58.0 0.005 c
≥190 249 75.9 69.1 79.9 <0.001 b 24 54.2 66.7 58.3 0.097

Note: Values shown are n/N in group (%).

Abbreviations: DLDL, directly measured LDL‐cholesterol; EMLDL, LDL‐cholesterol estimated using extended Martin/Hopkins equation; FLDL, LDL‐cholesterol estimated using Friedewald equation; SLDL, LDL‐cholesterol estimated using Sampson equation; TG, triglyceride.

a

p values were calculated with Cochran's Q test.

b

FLDL versus EMLDL; EMLDL versus SLDL <0.05.

c

EMLDL versus SLDL <0.05.

d

FLDL versus EMLDL <0.05.

e

FLDL versus SLDL <0.05.

f

FLDL versus EMLDL; FLDL versus SLDL <0.05.

g

FLDL versus EMLDL; FLDL versus SLDL; EMLDL versus SLDL <0.05.