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. 2023 Nov 3;23:426. doi: 10.1186/s12890-023-02732-w

Table 1.

Clinical characteristics and imaging features in the patients with and without the CT-occult CLSCC and SEPL

CT-occult CLSCC and SEPL Non CT-occult CLSCC and SEPL p Value
n = 41 n = 48
Patient characteristics, number(%) or median(IQR)
 Sex (men) 41/41 (100.0%) 48/48 (100.0%)
 Age, years 62(10) 60.05(10) 0.083
 Ex-or-current smokers 35/41(85.4%) 30/48(62.5%) 0.015
 Pack-years ≥ 20 35/41(85.4%) 30/48(62.6%) 0.015
Laboratory examinations, median (IQR)
 CEA(ng/ml) 1.97(2.57) 1.285(1.62) 0.046
 CA125(U/ml) 10.4(8.85) 7.95(5.5) 0.011
 CA199(U/ml) 8.63(10.26) 9.99(7.32) 0.633
Radiological examinations, number (%)
 Other nodules 34(82.9%) 46(95.8%) 0.075
 Focal fibrosis 24(58.5%) 24(50%) 0.421
 Bulla 9(22%) 7(14.6%) 0.367
CT radiomics characteristics, number (%)
 Interval distribution 1 0.008
  [-950 ~ -850HU] 30(73.2%) 45(93.8%)
  [-850 ~ -750HU] 11(26.8%) 3(6.2%)
 Interval distribution 2 0.001
  [-950 ~ -900HU] 7(17.1%) 24(50%)
  [-900 ~ -850HU] 34(82.9%) 24(50%)

CT-occult CLSCC and SEPL CT-occult central lung squamous cell carcinoma and squamous epithelial precancerous lesions, LC lung cancer