Table 3.
Comparison of calculated parameters according to the 3 grades of paradoxical septal motion
| Normal Septal Motion Grade 0 (n = 162)a |
Transient septal flattening Grade 1 (n = 100)a |
Sustained septal flattening or inversed septal bulging Grade 2 (n = 48)a |
p-valueb | Adjusted p-valuec | |
|---|---|---|---|---|---|
| Difference between the partial area under the strain curve of septal or lateral segments and inferior or anterior segments (cm2) | |||||
| MAS-MA | − 110 ( − 260, 1) | − 11 ( − 155, 154) | 280 (73, 492) | < 0.001 | < 0.001 |
| MAS-MI | − 112 ( − 250, 1) | − 25 ( − 191, 100) | 237 (57, 390) | < 0.001 | < 0.001 |
| MIS-MA | − 84 ( − 209, 21) | − 1 ( − 174, 149) | 166 ( − 26, 360) | < 0.001 | < 0.001 |
| MIS_MI | − 99 ( − 237, 3) | − 15 ( − 195, 123) | 84 ( − 46, 321) | < 0.001 | < 0.001 |
| MAL-MA | − 72 ( − 208, 41) | − 7 ( − 166, 176) | 140 (6, 427) | < 0.001 | < 0.001 |
| MAL-MI | − 83 ( − 217, 15) | − 24 ( − 177, 129) | 91 ( − 20, 344) | < 0.001 | < 0.001 |
| MIL-MA | − 121 ( − 274, 0) | − 27 ( − 199, 109) | 254 (28, 463) | < 0.001 | < 0.001 |
| MIL-MI | − 121 ( − 270, − 8) | − 51 ( − 242, 69) | 238 (16, 381) | < 0.001 | < 0.001 |
| Difference of time between Time to peak of each segment and Aortic Valve Closure (% cycle) | |||||
| MAS-AVC | − 1 ( − 3, 2) | 0 ( − 3, 3) | 3 ( − 1, 8) | 0.005 | 0.005 |
| MIS-AVC | 0 ( − 3, 4) | 1 ( − 2, 6) | 3 (0, 11) | 0.001 | 0.002 |
| MAL-AVC | 0 ( − 3, 4) | 3 ( − 1, 7) | 3 (0, 10) | 0.002 | 0.002 |
| MIL-AVC | − 2 ( − 3, 2) | 0 ( − 3, 3) | 3 (0, 9) | < 0.001 | < 0.001 |
| MA-AVC | − 1 ( − 3, 4) | 0 ( − 3, 2) | 0 ( − 4, 2) | 0.6 | 0.6 |
| MI-AVC | − 1 ( − 3, 6) | 0 ( − 3, 3) | 0 ( − 4, 2) | 0.5 | 0.5 |
| Difference of Time to peak between septal or lateral segments and inferior or anterior segments (% cycle) | |||||
| MAS-MA | 0 (0, 0) | 0 (0, 3) | 2 (0, 10) | < 0.001 | < 0.001 |
| MAS-MI | 0 (0, 0) | 0 (0, 3) | 1 (0, 10) | < 0.001 | < 0.001 |
| MIS-MA | 0 (0, 0) | 0 (0, 4) | 3 (0, 11) | < 0.001 | < 0.001 |
| MIS-MI | 0 (0, 0) | 0 (0, 3) | 3 (0, 10) | < 0.001 | < 0.001 |
| MAL-MA | 0 (0, 0) | 0 (0, 4) | 3 (0, 10) | < 0.001 | < 0.001 |
| MAL-MI | 0 (0, 0) | 0 (0, 4) | 3 (0, 10) | < 0.001 | < 0.001 |
| MIL-MA | 0 ( − 1, 0) | 0 (0, 0) | 3 (0, 10) | < 0.001 | < 0.001 |
| MIL-MI | 0 ( − 2, 0) | 0 (0, 0) | 2 (0, 9) | < 0.001 | < 0.001 |
aMedian (IQR)
bKruskal–Wallis rank sum test
cFalse discovery rate correction for multiple testing
AVC: Aortic valve closure; MAS: Mid-anteroseptal; MIS: Mid-infero-septal; MAL: Mid-anterolateral; MIL: Mid-inferolateral; MA: Mid-anterior; MI: Mid-inferior