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. 2023 Nov 2;21:404. doi: 10.1186/s12951-023-02170-0

Fig. 6.

Fig. 6

Safety assessment of ROD therapy (n = 5). A Liver and renal function were tested 7 days after treatments. B HE staining of the heart, liver, spleen, lung, and kidney samples (×20 magnification). C Mice body weight at the indicated times after different treatments. These results presented that ROD treatment have no additional damage to mice. BUN blood urea nitrogen, Cre creatinine, AST aspartate aminotransferase, ALT alanine aminotransferase. Ns not significant