Figure 4.
Long-term potentiation of synaptic transmission in area CA1 of the hippocampus is much improved by DA4-JC. A 2-way ANOVA found an overall difference between groups (p < 0.001) and over time (P < 0.001). The APP/PS1 DA4-JC group is significantly different from the other 3 groups. The APP/PS1 saline group is significantly different from the wild type (p < 0.001) and the APP/PS1 liraglutide group (p < 0.01). N = 6 per group.