Table 1. Comparison of diagnostic sensitivities and specificities of the standard Two-Tier test, the Immunetics® C6 Lyme ELISA™, and the MicroB-plex Anti-C6 Immunoassay using the 32 sample reference set CDC Lyme Serum Panel I.

Measure	Standard Two-Tier Test*	Immunetics Anti-C6 (Serum 1:21)	MicroB-plex Anti-C6 (Serum 1:1000)
Concordance with Standard Two-Tier Serology Results
Sensitivity	100% (8/8)	100% (8/8)	100% (8/8)
Specificity	100% (24/24)	100% (24/24)	100% (24/24)
Identification of Past or Present Lyme Disease
Sensitivity	67% (8/12)	67% (8/12)	67% (8/12)
Specificity	100% (20/20)	100% (20/20)	100% (20/20)

* Reference assay performed by CDC