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. 2023 Nov 3;9(44):eadi7337. doi: 10.1126/sciadv.adi7337

Fig. 7. Effects of flora on the ability of HFDF to prevent placental inflammation and suppress insulin resistance during pregnancy.

Fig. 7.

(A) Illustration of antibiotic (ABX) experiment. Results represent two independent experiments. (B and I) Serum LPS level of ABX experiment and FMT experiment (n = 6 mice per group). (C and J) Placental LPS level of ABX experiment and FMT experiment (n = 6 placentae from 6 litters per group). (D and K) Serum TNF-α level of ABX experiment and FMT experiment (n = 6 mice per group). (E and L) Placental TNF-α level of ABX experiment and FMT experiment (n = 6 placentae from 6 litters per group). (F and M) GTT of ABX and FMT experiment (n = 6 mice per group). (G and N) ITT of ABX and FMT experiment (n = 6 mice per group). (H) Illustration of FMT experiment. Data were analyzed by unpaired Student’s t test with Welch’s correction [(B) to (E)], one-way ANOVA followed by post hoc Tukey’s tests (I to L), or two-way ANOVA followed by post hoc Bonferroni tests (GTT and ITT) and represented means ± SEM. #P < 0.05, ** or ##P < 0.01, and *** or ###P < 0.001, relative to chow and GDM group, respectively.