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. 2023 May 28;3(4):20210111. doi: 10.1002/EXP.20210111

FIGURE 9.

FIGURE 9

Cyclodextrin‐based responsive supramolecular linkers. Schematics of A) HCJSP nanoparticle preparation and B) combinational therapy mechanism. C) Release profiles of JQ1 from HCJSP nanoparticles. D) Western blot assay of LDHA, c‐Myc, HK‐2, and BRD4 expression after JQ1 treatment. E) Flow cytometry analysis of PD‐L1 expression after stimulation of IFN‐γ/JQ1. F) Antitumor effect and G) anti‐metastasis effect of various formulations in vivo. Reproduced with permission.[ 49 ] Copyright 2021, Wiley‐VCH. H) Schematics of (a) fabrication of PDA‐Pt‐CD@RuFc NPs and (b) expected mechanisms of PDA‐Pt‐CD@RuFc NPs. I) Release profiles under different stimuli. J) Antitumor efficiency of PDA‐Pt‐CD@RuFc NPs in vivo. Reproduced with permission.[ 50 ] Copyright 2020, Wiley‐VCH.