Table 3.

Association of a doubling in estimated serum-PFAS concentration at three different infancy ages with a change (in %) in serum concentrations of leptin, adiponectin, and resistin at 9 years, with confidence intervals (CI) and probability (p) values, also for sex interaction in the 298 members of the birth cohort.

		Leptin				Adiponectin				Resistin
PFAS	Age in months	Change	95% CI	p	psex	Change	95% CI	p	psex	Change	95% CI	p	psex
PFOS	3	12.2	−5.20; 32.8	0.18	0.10	5.31	−3.28; 14.7	0.23	0.68	−8.59	−17.5; 1.29	0.09	0.97
	6	11.8	−3.43; 29.4	0.14	0.17	6.34	−1.22; 14.5	0.10	0.71	−11.6	−19.1; -3.39	0.007	0.80
	12	8.38	−3.70; 22.0	0.18	0.37	4.85	−1.22; 11.3	0.12	0.69	−9.92	−16.1; -3.26	0.004	0.26
PFOA	3	−6.96	−19.6; 7.60	0.33	0.92	3.67	−3.70; 11.6	0.34	0.65	−8.82	−16.6; −0.34	0.04	0.75
	6	−3.82	−15.6; 9.55	0.56	0.89	4.84	−1.85; 12.0	0.16	0.71	−11.3	−18.0; −3.98	0.003	0.89
	12	−2.04	−12.2; 9.31	0.71	0.76	4.06	−1.54; 10.0	0.16	0.86	−10.0	−15.8; −3.89	0.002	0.54
PFHxS	3	9.32	−2.44; 22.5	0.13	0.41	5.63	−0.31; 11.9	0.06	0.85	−3.30	−9.79; 3.65	0.34	0.41
	6	7.32	−1.96; 17.5	0.13	0.57	5.04	0.33; 9.96	0.04	0.90	−5.88	−10.9; −0.53	0.032	0.67
	12	4.40	−2.45; 11.7	0.21	0.82	3.16	−0.31; 6.75	0.08	0.98	−4.61	−8.47; −0.59	0.025	0.55
PFDA	3	11.1	−12.2; 40.5	0.38	0.23	6.61	−5.32; 20.0	0.29	0.91	−11.1	−23.0; 2.60	0.11	0.66
	6	13.0	−9.28; 40.7	0.28	0.29	8.31	−3.04; 21.0	0.16	0.99	−15.7	−26.2; −3.66	0.012	0.77
	12	9.74	−8.06; 31.0	0.30	0.46	5.96	−3.09; 15.8	0.20	0.80	−13.7	−22.5; −3.95	0.007	0.49
PFNA	3	6.34	−11.4; 27.7	0.51	0.11	3.66	−5.49; 13.7	0.45	0.89	−13.7	−22.8; −3.61	0.009	0.60
	6	7.55	−8.30; 26.1	0.37	0.17	5.20	−2.94; 14.0	0.22	0.99	−16.0	−23.7; −7.58	<0.001	0.61
	12	5.56	−6.71; 19.4	0.39	0.37	3.84	−2.44; 10.5	0.24	0.86	−12.5	−18.8; −5.80	<0.001	0.17

Bold numbers indicate statistically significant results.