Table 3.
Associations between immune cell subtype cluster and breast cancer survival.
| Dataset | Relapse-free survival | Overall survival | Relapse-free survival* | Overall survival* | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | |
| METABRIC | 0.001 | < 0.001 | 0.009 | 0.011 | ||||||||
| Cluster A | 1 | 1 | 1 | 1 | ||||||||
| Cluster B | 1.42 | 1.15–1.74 | 1.60 | 1.28–2.00 | 1.38 | 1.08–1.76 | 1.37 | 1.08–1.75 | ||||
| Turin study | 0.028 | 0.114 | 0.154 | 0.358 | ||||||||
| Cluster A | 1 | 1 | 1 | 1 | ||||||||
| Cluster B | 1.87 | 1.07–3.27 | 1.74 | 0.85–3.47 | 1.53 | 0.85–2.73 | 1.40 | 0.68–2.89 | ||||
| TCGA# | 0.072 | 0.017 | 0.002 | 0.004 | ||||||||
| Cluster A | 1 | 1 | 1 | 1 | ||||||||
| Cluster B | 1.54 | 0.96–2.47 | 1.63 | 1.09–2.43 | 2.24 | 1.34–3.74 | 1.93 | 1.24–3.01 | ||||
*Adjusted for age, stage, grade, ER, PR, and histology.
#Tumor grade not included in multivariate analysis.
Significant values are in bold.