Fig. 2.

Associations of CGM-derived features with pregnancy outcomes. Forest plot presents the ORs (95% CI) of any adverse pregnancy outcome or each individual pregnancy outcome per standardized change of CGM-derived metrics (in SD unit). The case number of each outcome and the number of total participants were annotated as “(case/total)”. False discovery rate (FDR) was corrected based on Benjamini–Hochberg method. ∗FDR <0.05. Any adverse pregnancy outcome was defined as the prevalence of one or more of the following conditions: preterm birth, LGA, fetal distress, PROM, and NICU admission. Abbreviations: CGM, continuous glucose monitoring; OR, odds ratio; CI, confidence interval; TIR, time in range; TAR, time above range; TBR, time below range; AUC, glucose area under the curve; MBG, mean blood glucose; MAGE, mean amplitude of glucose excursions; CV, coefficient of variation; LGA, large for gestational age; PROM, premature rupture of fetal membranes; NICU, neonatal intensive care unit.