Fig. 5.

The EPS was the functional component of EPS from lacticaseibacillus to the antiviral infection of PEDV with the STAT3 in the cell nucleus, which robust the mRNA transcription of anti-inflammatory and anti-viral genes, such as IL-10 and IFN-λ. The B indicated that the EPS did not specifically stimulate the IL-10 single pathways, and enhance the expression STAT3 with the PEDV infection. The C explained the higher expression of STAT3 with the EPS stimulation with the PEDV infection comparing with other groups in the IPEC-J2. The EPS from the lacticaseibacillus stimulate the STAT3 in the cell nucleus, which specifically robust the mRNA transcription and expression of anti-viral genes with IFN-λ in the F